New findings from a phase 1 study investigating two formulations of once-yearly intramuscular (IM) lenacapvir for HIV preoperative prophylaxis (PrEP) were discussed at the 2025 Conference on Retroviruses and Opportunistic Infections. The results, published simultaneously in The Lancet, represent a major advance in the fight against HIV and could open new avenues for long-term prevention….

1. What is U=U?  U=U is an abbreviation for the following phrase: Undetectable viral load = Unable to transmit the virus This means that if a person living with HIV achieves an undetectable HIV viral load through antiretroviral therapy (ART), they will not transmit HIV even if they do not use condoms or take preventive…

A study presented at the 2024 HIV Drug Therapeutics Conference in Glasgow suggests that two broadly neutralizing antibodies (bnAbs), teropavimab and zinlirvimab, could be effective partners alongside lenacapavir in long-acting HIV treatments. The results emphasize the significance of screening for antibody sensitivity in HIV, while also proposing that people with partial resistance might still benefit…

Briggs and researchers at the Max Planck Institute for Biochemistry have discovered the mechanism behind a crucial step in the HIV life cycle. In collaboration with teams from Heidelberg University and Yale University, they revealed that the mysterious “spacer peptide 2” (one of the HIV viral components) plays a key role in transforming immature HIV-1…

Luca Guadagnino, a renowned director behind Call Me by Your Name and Challengers, now brings us into a new romantic world in Queer, adapted from the deeply personal work of William S. Burroughs. The result? A unique, striking film that stands out in its own right. Set in 1950s Mexico, the film follows William Lee…

For his first short film as director, Frédéric Lavigne hits hard and right in the heart with the hyper sensitive Coeurs perdus .  Paris, 1992. Julien (Guillaume Soubeyran) is a science thesis student. A bisexual who doesn’t really accept himself, he logs on to a gay phone line from time to time to have anonymous encounters. It is through…

Zhao, a paraplegic man from Jilin, was sentenced to serve his sentence in Siping Prison on January 15, 2009 for robbery and attempted murder. He tested positive for HIV antibodies in prison in June 2011. Zhao and his family believed that the prison management had problems that led to his infection, and filed an administrative…

Premier long-métrage du réalisateur Andy Vallentine, A l’horizon (titre original The Mattachine Family) raconte le parcours d’un trentenaire gay confronté à sa quête de paternité. Un film touchant et sincère, aux accents de vécu personnel. Résumé de A l’horizon (The Mattachine Family) : Thomas (incarné par le séduisant Nico Tortorella), photographe trentenaire, a consacré sa…

Depuis plus de dix ans, Noel Alejandro a su se faire un nom dans l’univers du cinéma, en s’imposant comme un réalisateur unique en son genre. Ses débuts, marqués par des courts-métrages parfois perçus comme du cinéma X gay d’auteur, l’ont progressivement conduit à un statut de cinéaste reconnu. Sa carrière s’est enrichie d’œuvres éclectiques…

Jenny Blake Isabella, the creator of DC Comics’ Black Lightning, has publicly come out as transgender. She shared this news in a blog post on her personal website, where she also addressed questions from fans. While she prefers to be called Jenny, Isabella clarified that she doesn’t view her previous name, Tony Isabella, as a…

According to the Prison Policy Initiative, LGBTQ+ individuals face arrest rates more than double those of their straight counterparts, with lesbian and bisexual women being over four times more likely to be arrested than straight women. Additionally, one in six transgender people have experienced incarceration at some point in their lives. Tony Vick is currently…

The last independent ruler, or kabaka, of the Buganda kingdom—now part of Uganda—was King Mwanga II, who has been a central figure in a propaganda battle since his reign began in 1884. Known for his relationships with both male and female lovers, critics have labeled him a deranged, murderous deviant, while supporters portray him as…